Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50109383 (1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis | Bioorg Med Chem Lett 23: 6920-6922 (2013) Article DOI: 10.1016/j.bmcl.2013.09.038 BindingDB Entry DOI: 10.7270/Q2J969B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50109383 (1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity of the compound for sigma-1 receptor by displacing [3H]-(+) pentazocine | Bioorg Med Chem Lett 12: 497-500 (2002) BindingDB Entry DOI: 10.7270/Q2CN7365 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50109383 (1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of [3H](+)-pentazocin from rat brain membrane sigma 1receptor after 120 mins | Bioorg Med Chem Lett 20: 2564-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.087 BindingDB Entry DOI: 10.7270/Q2833S6G | |||||||||||
More data for this Ligand-Target Pair |