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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50157875'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157875
PNG
(CHEMBL3786776)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C23H31N3O/c1-18-12-15-26(16-13-18)14-7-17-27-23-20-10-5-6-11-21(20)24-22(25-23)19-8-3-2-4-9-19/h2-4,8-9,18H,5-7,10-17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 26n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair