BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Small conductance calcium-activated potassium channel protein 3' and Ligand = 'BDBM50061977'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 3 (Rattus norvegicus)	BDBM50061977 (17,25-diazonia-2,9-diazaheptacyclo[23.6.2.24,7.210...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by ChEMBL					Assay Description Displacement of [I125]apamine from Wistar rat recombinant SK3 channel expressed in HEK293 cells				J Med Chem 51: 7625-34 (2009) Article DOI: 10.1021/jm800809f BindingDB Entry DOI: 10.7270/Q28S4QT0
NeuroSearch A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 3 (Rattus norvegicus)	BDBM50061977 (17,25-diazonia-2,9-diazaheptacyclo[23.6.2.24,7.210...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by ChEMBL					Assay Description Inhibition of Wistar rat recombinant SK3 channel expressed in HEK293 cells by whole cell patch clamp technique				J Med Chem 51: 7625-34 (2009) Article DOI: 10.1021/jm800809f BindingDB Entry DOI: 10.7270/Q28S4QT0
NeuroSearch A/S Curated by ChEMBL					More data for this Ligand-Target Pair