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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2 (SGLT2)' and Ligand = 'BDBM228482'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2 (SGLT2)


(Homo sapiens (Human))
BDBM228482
PNG
(US9340521, E029)
Show SMILES COc1ccc(Cc2cc([C@@H]3O[C@H](SO)[C@@H](O)[C@H](O)[C@H]3O)c3OCCCc3c2Cl)cc1 |r|
Show InChI InChI=1/C22H25ClO7S/c1-28-13-6-4-11(5-7-13)9-12-10-15(20-14(16(12)23)3-2-8-29-20)21-18(25)17(24)19(26)22(30-21)31-27/h4-7,10,17-19,21-22,24-27H,2-3,8-9H2,1H3/t17-,18-,19+,21+,22-/s2
UniProtKB/SwissProt

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GoogleScholar
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KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a 0.470n/an/an/an/a7.437



GREEN CROSS CORPORATION

US Patent


Assay Description
For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...


US Patent US9340521 (2016)


BindingDB Entry DOI: 10.7270/Q2TQ60CH
More data for this
Ligand-Target Pair