Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Sciences Center Curated by ChEMBL | Assay Description Inhibition of human CNT2 | Bioorg Med Chem Lett 19: 917-21 (2009) Article DOI: 10.1016/j.bmcl.2008.11.112 BindingDB Entry DOI: 10.7270/Q2K07440 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill... | ACS Med Chem Lett 6: 244-8 (2015) Article DOI: 10.1021/ml500343r BindingDB Entry DOI: 10.7270/Q2BK1F27 | |||||||||||
More data for this Ligand-Target Pair |