Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human)) | BDBM50008745 (CHEMBL3236329) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human Nav1.8 assessed as inactivated-state block using double pulse protocol by patch-clamp electrophysiology/cell based assay | J Med Chem 57: 2942-52 (2014) Article DOI: 10.1021/jm401881q BindingDB Entry DOI: 10.7270/Q2CZ38QJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human)) | BDBM50008745 (CHEMBL3236329) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human Nav1.8 assessed as 10 Hz block using double pulse protocol by patch-clamp electrophysiology/cell based assay | J Med Chem 57: 2942-52 (2014) Article DOI: 10.1021/jm401881q BindingDB Entry DOI: 10.7270/Q2CZ38QJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human)) | BDBM50008745 (CHEMBL3236329) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human Nav1.8 assessed as tonic block using double pulse protocol by patch-clamp electrophysiology/cell based assay | J Med Chem 57: 2942-52 (2014) Article DOI: 10.1021/jm401881q BindingDB Entry DOI: 10.7270/Q2CZ38QJ | |||||||||||
More data for this Ligand-Target Pair |