Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM263408'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM263408 ((R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3...) Show SMILES NC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(C2)c2cc(Cl)cc(Cl)c2)cc1F |r| Show InChI InChI=1S/C21H21Cl2FN2O2/c22-13-6-14(23)8-15(7-13)26-5-1-2-16(11-26)28-20-10-19(24)18(21(25)27)9-17(20)12-3-4-12/h6-10,12,16H,1-5,11H2,(H2,25,27)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM263408 ((R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3...) Show SMILES NC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(C2)c2cc(Cl)cc(Cl)c2)cc1F |r| Show InChI InChI=1S/C21H21Cl2FN2O2/c22-13-6-14(23)8-15(7-13)26-5-1-2-16(11-26)28-20-10-19(24)18(21(25)27)9-17(20)12-3-4-12/h6-10,12,16H,1-5,11H2,(H2,25,27)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM263408 ((R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3...) Show SMILES NC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(C2)c2cc(Cl)cc(Cl)c2)cc1F |r| Show InChI InChI=1S/C21H21Cl2FN2O2/c22-13-6-14(23)8-15(7-13)26-5-1-2-16(11-26)28-20-10-19(24)18(21(25)27)9-17(20)12-3-4-12/h6-10,12,16H,1-5,11H2,(H2,25,27)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
					More data for this Ligand-Target Pair