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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM343027'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM343027
PNG
(1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-...)
Show SMILES COc1cc(c(Cl)cc1-c1nn(C)c(=O)c2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cccc(F)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of amyloid-beta production in Chinese hamster ovary (CHO) cells expressing human amyloid precursor protein (APP)


J Med Chem 60: 5969-5989 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01851
BindingDB Entry DOI: 10.7270/Q2RJ4MS7
More data for this
Ligand-Target Pair
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM343027
PNG
(1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-...)
Show SMILES COc1cc(c(Cl)cc1-c1nn(C)c(=O)c2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cccc(F)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Amgen Inc.

US Patent




US Patent US9776995 (2017)


BindingDB Entry DOI: 10.7270/Q2Q81G6R
More data for this
Ligand-Target Pair