Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM50237511'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50237511 (CHEMBL4072007) Show SMILES CN[C@H]1CC[C@@](CCOc2cc(F)c(cc2F)S(=O)(=O)Nc2ncns2)(CC1)c1ccccc1 |r,wU:5.5,2.1,(27.81,-33.45,;26.5,-32.64,;26.55,-31.1,;25.25,-30.29,;25.3,-28.76,;26.65,-28.04,;27.42,-26.71,;28.96,-26.72,;29.72,-28.06,;31.26,-28.06,;32.03,-26.74,;33.56,-26.74,;34.33,-25.41,;34.33,-28.09,;33.55,-29.41,;32.02,-29.41,;31.24,-30.73,;35.87,-28.09,;36.28,-26.6,;37.37,-27.7,;36.63,-29.43,;38.17,-29.43,;39.08,-28.19,;40.54,-28.67,;40.54,-30.21,;39.07,-30.68,;27.96,-28.83,;27.91,-30.38,;25.55,-26.94,;25.96,-25.43,;24.86,-24.33,;23.35,-24.73,;22.95,-26.25,;24.05,-27.34,)| Show InChI InChI=1S/C23H26F2N4O3S2/c1-26-17-7-9-23(10-8-17,16-5-3-2-4-6-16)11-12-32-20-13-19(25)21(14-18(20)24)34(30,31)29-22-27-15-28-33-22/h2-6,13-15,17,26H,7-12H2,1H3,(H,27,28,29)/t17-,23-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5 expressed in HEK293 cells assessed as reduction in peak inward current at -50 mV holding potential measured af...				J Med Chem 60: 2513-2525 (2017) Article DOI: 10.1021/acs.jmedchem.6b01918 BindingDB Entry DOI: 10.7270/Q2057J69
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