Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM309373 ((S)-2-Amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pri...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma L.P. US Patent | Assay Description In the alternative, the voltage clamp protocol to examine hNav1.7 currents was as follows. First, the standard current-voltage relationship was teste... | US Patent US9656959 (2017) BindingDB Entry DOI: 10.7270/Q2TF00FC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM309373 ((S)-2-Amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pri...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma L.P. US Patent | Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access... | US Patent US9656959 (2017) BindingDB Entry DOI: 10.7270/Q2TF00FC | |||||||||||
More data for this Ligand-Target Pair |