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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type X alpha subunit' and Ligand = 'BDBM50231784'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type X alpha subunit


(Mus musculus)
BDBM50231784
PNG
(CHEMBL251067 | [5-(4-Chlorophenyl)furan-2-yl-(4-di...)
Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C18H21ClN2O2/c1-20(2)15-9-11-21(12-10-15)18(22)17-8-7-16(23-17)13-3-5-14(19)6-4-13/h3-8,15H,9-12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay


J Med Chem 51: 407-16 (2008)


Article DOI: 10.1021/jm070637u
BindingDB Entry DOI: 10.7270/Q2KK9CN7
More data for this
Ligand-Target Pair
Sodium channel protein type X alpha subunit


(Mus musculus)
BDBM50231784
PNG
(CHEMBL251067 | [5-(4-Chlorophenyl)furan-2-yl-(4-di...)
Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C18H21ClN2O2/c1-20(2)15-9-11-21(12-10-15)18(22)17-8-7-16(23-17)13-3-5-14(19)6-4-13/h3-8,15H,9-12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant Nav1.8 channel expressed in HEK293 cells by isotopic efflux assay


Bioorg Med Chem 16: 6379-86 (2008)


Article DOI: 10.1016/j.bmc.2008.05.003
BindingDB Entry DOI: 10.7270/Q2VH5NNT
More data for this
Ligand-Target Pair