Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50055017 (7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-im...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.05 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cells | J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50055017 (7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-im...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT) | J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50055017 (7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-im...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brain | J Med Chem 39: 4935-41 (1997) Article DOI: 10.1021/jm960288w BindingDB Entry DOI: 10.7270/Q2ZK5FSR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50055017 (7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-im...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membrane | J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50055017 (7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-im...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program/NIH Curated by ChEMBL | Assay Description Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissue | J Med Chem 45: 4119-27 (2002) BindingDB Entry DOI: 10.7270/Q21Z43R6 | |||||||||||
More data for this Ligand-Target Pair |