Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50080827 ((2R,6S)-1-Methyl-2,6-diphenethyl-piperidine | (2S,...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by PDSP Ki Database | J Pharmacol Exp Ther 310: 1035-45 (2004) Article DOI: 10.1124/jpet.104.068098 BindingDB Entry DOI: 10.7270/Q2WH2NJN | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50080827 ((2R,6S)-1-Methyl-2,6-diphenethyl-piperidine | (2S,...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of DAT in rat striatal synaptosomes assessed as reduction of [3H]dopamine uptake preincubated for 5 mins followed by [3H]dopamine addition... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair |