Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50262411 ((S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation counting | Bioorg Med Chem Lett 19: 5078-81 (2009) Article DOI: 10.1016/j.bmcl.2009.07.049 BindingDB Entry DOI: 10.7270/Q2JQ115V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50262411 ((S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cells | Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50262411 ((S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation counting | Bioorg Med Chem Lett 18: 4308-11 (2008) Article DOI: 10.1016/j.bmcl.2008.06.078 BindingDB Entry DOI: 10.7270/Q2Q2401S | |||||||||||
More data for this Ligand-Target Pair |