BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 1' and Ligand = 'BDBM50367247'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 22 member 1 (RAT)	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bayerische Julius-Maximilians-Universit£t Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytes				Nature 372: 549-552 (1994) Article DOI: 10.1038/372549a0 BindingDB Entry DOI: 10.7270/Q2B56M05
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Heidelberg Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake in OCT1-expressing HEK293 cells				Naunyn Schmiedebergs Arch Pharmacol 354: 320-6 (1997) Article DOI: 10.1007/bf00171063 BindingDB Entry DOI: 10.7270/Q2MG7QSP
University of Heidelberg Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PubMed	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing HeLa cells				J Pharmacol Exp Ther 286: 354-61 (1998) BindingDB Entry DOI: 10.7270/Q28P63DW
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Mus musculus)	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes				Biochem Biophys Res Commun 296: 644-50 (2002) BindingDB Entry DOI: 10.7270/Q2P84D6R
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Manitoba Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cells				J Pharmacol Exp Ther 303: 959-68 (2002) Article DOI: 10.1124/jpet.102.038885 BindingDB Entry DOI: 10.7270/Q28W3FTB
University of Manitoba Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manitoba Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cells				J Pharmacol Exp Ther 303: 959-68 (2002) Article DOI: 10.1124/jpet.102.038885 BindingDB Entry DOI: 10.7270/Q28W3FTB
University of Manitoba Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Anatomy of the Bayerische Julius-Maximilians-Universit£t Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes				Am J Physiol Renal Physiol 281: 454-68 (2001) Article DOI: 10.1152/ajprenal.2001.281.3.F454 BindingDB Entry DOI: 10.7270/Q2BR8TF3
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50367247 (QUININE \| Quinamm \| Quinsan \| cid_3034034) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy				J Med Chem 51: 5932-42 (2008) Article DOI: 10.1021/jm8003152 BindingDB Entry DOI: 10.7270/Q23779MD
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair