BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 1' and Ligand = 'BDBM50416487'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 22 member 1 (Mus musculus)	BDBM50416487 (CHEMBL1236196 \| TETRABUTYLAMMONIUM) Show SMILES CCCC[N+](CCCC)(CCCC)CCCC Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes				J Pharmacol Exp Ther 292: 1146-52 (2000) BindingDB Entry DOI: 10.7270/Q2XS5WPJ
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50416487 (CHEMBL1236196 \| TETRABUTYLAMMONIUM) Show SMILES CCCC[N+](CCCC)(CCCC)CCCC Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes				J Pharmacol Exp Ther 292: 1146-52 (2000) BindingDB Entry DOI: 10.7270/Q2XS5WPJ
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50416487 (CHEMBL1236196 \| TETRABUTYLAMMONIUM) Show SMILES CCCC[N+](CCCC)(CCCC)CCCC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PubMed	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes				J Pharmacol Exp Ther 292: 1146-52 (2000) BindingDB Entry DOI: 10.7270/Q2XS5WPJ
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50416487 (CHEMBL1236196 \| TETRABUTYLAMMONIUM) Show SMILES CCCC[N+](CCCC)(CCCC)CCCC Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayerische Julius-Maximilians-Universit£t Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes				Mol Pharmacol 56: 1254-61 (1999) Article DOI: 10.1124/mol.56.6.1254 BindingDB Entry DOI: 10.7270/Q2M90CJ1
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50416487 (CHEMBL1236196 \| TETRABUTYLAMMONIUM) Show SMILES CCCC[N+](CCCC)(CCCC)CCCC Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 50 uM) in OCT1-expressing MDCK cells				Pharm Res 18: 1528-34 (2001) BindingDB Entry DOI: 10.7270/Q28G8N0T
Kyoto University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50416487 (CHEMBL1236196 \| TETRABUTYLAMMONIUM) Show SMILES CCCC[N+](CCCC)(CCCC)CCCC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in OCT1-expressing HeLa cells				J Pharmacol Exp Ther 288: 1192-8 (1999) BindingDB Entry DOI: 10.7270/Q24X5BNQ
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair