BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 12' and Ligand = 'BDBM318953'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318953
PNG
(1-[[7-(4-Cyanophenyl)-3-methylbenzo[d]isothiazol-6...)
Show SMILES Cc1nsc2c(c(SC3(CCC3)C(O)=O)ccc12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C20H16N2O2S2/c1-12-15-7-8-16(25-20(19(23)24)9-2-10-20)17(18(15)26-22-12)14-5-3-13(11-21)4-6-14/h3-8H,2,9-10H2,1H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.43E+3n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair