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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 12' and Ligand = 'BDBM318957'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318957
PNG
(1-[[7-(4-Cyanophenyl)benzo[d]isothazol-6-yl]thio]c...)
Show SMILES OC(=O)C1(CCCCC1)Sc1ccc2cnsc2c1-c1ccc(cc1)C#N
Show InChI InChI=1S/C21H18N2O2S2/c22-12-14-4-6-15(7-5-14)18-17(9-8-16-13-23-27-19(16)18)26-21(20(24)25)10-2-1-3-11-21/h4-9,13H,1-3,10-11H2,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 296n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair