BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 6' and Ligand = 'BDBM50009999'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 22 member 6 (Rattus norvegicus)	BDBM50009999 (CHEMBL461 \| N-benzoylglycine) Show SMILES OC(=O)CNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat Oat1 expressed in pig LLC-PK11 cells				Bioorg Med Chem 19: 3320-40 (2011) Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Mus musculus)	BDBM50009999 (CHEMBL461 \| N-benzoylglycine) Show SMILES OC(=O)CNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat1 expressed in Xenopus oocytes				Bioorg Med Chem 19: 3320-40 (2011) Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Mus musculus)	BDBM50009999 (CHEMBL461 \| N-benzoylglycine) Show SMILES OC(=O)CNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50009999 (CHEMBL461 \| N-benzoylglycine) Show SMILES OC(=O)CNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human Oat1 expressed in HEK293 cells				Bioorg Med Chem 19: 3320-40 (2011) Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50009999 (CHEMBL461 \| N-benzoylglycine) Show SMILES OC(=O)CNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Women's Medical University Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT-expressing OK cells				Br J Pharmacol 135: 555-63 (2002) Article DOI: 10.1038/sj.bjp.0704482 BindingDB Entry DOI: 10.7270/Q21J9C29
Tokyo Women's Medical University Curated by ChEMBL					More data for this Ligand-Target Pair