new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 2' and Ligand = 'BDBM144770'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM144770
PNG
(US8952128, 28A)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@@H](Cc1ccc(O)cc1)NCCCN(C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)C(C)=O |r|
Show InChI InChI=1/C90H117FN18O11/c1-55(110)81-89(120)106-75(47-60-30-34-64(91)35-31-60)82(113)96-39-15-13-26-72(100-52-65(43-59-32-36-66(112)37-33-59)95-41-18-42-109(56(2)111)54-61-44-69-68-24-16-28-71-80(68)63(51-99-71)49-79(69)108(3)53-61)83(114)101-74(29-17-40-97-90(93)94)84(115)103-76(45-57-19-6-4-7-20-57)86(117)104-77(46-58-21-8-5-9-22-58)87(118)105-78(48-62-50-98-70-25-11-10-23-67(62)70)88(119)102-73(85(116)107-81)27-12-14-38-92/h4-11,16,19-25,28,30-37,50-51,55,61,65,69,72-79,81,95,98-100,110,112H,12-15,17-18,26-27,29,38-49,52-54,92H2,1-3H3,(H,96,113)(H,101,114)(H,102,119)(H,103,115)(H,104,117)(H,105,118)(H,106,120)(H,107,116)(H4,93,94,97)/t55-,61-,65-,69-,72-,73+,74+,75+,76+,77+,78-,79-,81+/s2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.0400 -59.3n/an/an/an/an/a7.625



Ipsen Pharma S.A.S.

US Patent


Assay Description
Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...


US Patent US8952128 (2015)


BindingDB Entry DOI: 10.7270/Q2057DNG
More data for this
Ligand-Target Pair