Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 4' and Ligand = 'BDBM275984'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275984 (US10071974, Example 95 | US10577336, Example 95) Show SMILES Cc1cccn2c(ncc12)C(C)(C)NC(=O)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C16H22N4O2/c1-11-5-4-7-20-12(11)9-18-15(20)16(2,3)19-14(21)13-10-17-6-8-22-13/h4-5,7,9,13,17H,6,8,10H2,1-3H3,(H,19,21)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	218	-38.0	n/a	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10071974 (2018) BindingDB Entry DOI: 10.7270/Q28G8NQ7
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275984 (US10071974, Example 95 | US10577336, Example 95) Show SMILES Cc1cccn2c(ncc12)C(C)(C)NC(=O)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C16H22N4O2/c1-11-5-4-7-20-12(11)9-18-15(20)16(2,3)19-14(21)13-10-17-6-8-22-13/h4-5,7,9,13,17H,6,8,10H2,1-3H3,(H,19,21)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	218	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10577336 (2020) BindingDB Entry DOI: 10.7270/Q24F1T4F
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275984 (US10071974, Example 95 | US10577336, Example 95) Show SMILES Cc1cccn2c(ncc12)C(C)(C)NC(=O)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C16H22N4O2/c1-11-5-4-7-20-12(11)9-18-15(20)16(2,3)19-14(21)13-10-17-6-8-22-13/h4-5,7,9,13,17H,6,8,10H2,1-3H3,(H,19,21)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10577336 (2020) BindingDB Entry DOI: 10.7270/Q24F1T4F
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275984 (US10071974, Example 95 | US10577336, Example 95) Show SMILES Cc1cccn2c(ncc12)C(C)(C)NC(=O)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C16H22N4O2/c1-11-5-4-7-20-12(11)9-18-15(20)16(2,3)19-14(21)13-10-17-6-8-22-13/h4-5,7,9,13,17H,6,8,10H2,1-3H3,(H,19,21)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.5	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...				US Patent US10071974 (2018) BindingDB Entry DOI: 10.7270/Q28G8NQ7
					More data for this Ligand-Target Pair