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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 4' and Ligand = 'BDBM312048'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM312048
PNG
(US10166214, Example 184 | US10675268, Example 184)
Show SMILES Cc1cccn2c(ccc12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r|
Show InChI InChI=1S/C18H23N3O/c1-11-5-4-8-21-14(11)6-7-15(21)18(2,3)20-17(22)16-12-9-19-10-13(12)16/h4-8,12-13,16,19H,9-10H2,1-3H3,(H,20,22)/t12-,13+,16+
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.400n/an/an/an/a



Centrexion Therapeutics Corporation

US Patent


Assay Description
The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...


US Patent US10675268 (2020)


BindingDB Entry DOI: 10.7270/Q21C20XK
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM312048
PNG
(US10166214, Example 184 | US10675268, Example 184)
Show SMILES Cc1cccn2c(ccc12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r|
Show InChI InChI=1S/C18H23N3O/c1-11-5-4-8-21-14(11)6-7-15(21)18(2,3)20-17(22)16-12-9-19-10-13(12)16/h4-8,12-13,16,19H,9-10H2,1-3H3,(H,20,22)/t12-,13+,16+
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.400n/an/an/an/a



Centrexion Therapeutics Corporation

US Patent


Assay Description
The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...


US Patent US10166214 (2019)


BindingDB Entry DOI: 10.7270/Q2D50Q16
More data for this
Ligand-Target Pair