Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 4' and Ligand = 'BDBM50081059'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi...				ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	70.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	70.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	70.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10675268 (2020) BindingDB Entry DOI: 10.7270/Q21C20XK
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10675268 (2020) BindingDB Entry DOI: 10.7270/Q21C20XK
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50081059 (CHEMBL3421845 | US10166214, Example 138 | US106752...) Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r| Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i...				ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP
					More data for this Ligand-Target Pair