Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 46.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 46.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 46.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US10675268 (2020) BindingDB Entry DOI: 10.7270/Q21C20XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia... | US Patent US10675268 (2020) BindingDB Entry DOI: 10.7270/Q21C20XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081060 (CHEMBL3421844 | US10166214, Example 101 | US106752...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair |