Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Mus musculus (Mouse)) | BDBM50041982 (CHEMBL3359522) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Rattus norvegicus) | BDBM50041982 (CHEMBL3359522) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0720 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50041982 (CHEMBL3359522) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0250 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Macaca mulatta) | BDBM50041982 (CHEMBL3359522) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0380 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at monkey S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50041982 (CHEMBL3359522) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Canis lupus familiaris) | BDBM50041982 (CHEMBL3359522) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0490 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair |