Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50186936'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50186936 (3-(4-(5-(3-cyano-4-(1,1,1-trifluoropropan-2-yloxy)...) Show SMILES CC(Oc1ccc(cc1C#N)-c1nc(no1)-c1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C22H18F3N3O4/c1-12-9-14(4-8-19(29)30)3-6-17(12)20-27-21(32-28-20)15-5-7-18(16(10-15)11-26)31-13(2)22(23,24)25/h3,5-7,9-10,13H,4,8H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptake				Bioorg Med Chem Lett 16: 3679-83 (2006) Article DOI: 10.1016/j.bmcl.2006.04.084 BindingDB Entry DOI: 10.7270/Q2J67GJ8
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