Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50313347'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50313347 (6-(cyclohexyl(methyl)amino)-N-(1H-indazol-5-yl)pyr...) Show SMILES CN(C1CCCCC1)c1cc(ncn1)C(=O)Nc1ccc2[nH]ncc2c1 Show InChI InChI=1S/C19H22N6O/c1-25(15-5-3-2-4-6-15)18-10-17(20-12-21-18)19(26)23-14-7-8-16-13(9-14)11-22-24-16/h7-12,15H,2-6H2,1H3,(H,22,24)(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	418	n/a	n/a	n/a	n/a
Merck Serono SA Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assay				Bioorg Med Chem Lett 20: 1516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.102 BindingDB Entry DOI: 10.7270/Q2J38SQK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50313347 (6-(cyclohexyl(methyl)amino)-N-(1H-indazol-5-yl)pyr...) Show SMILES CN(C1CCCCC1)c1cc(ncn1)C(=O)Nc1ccc2[nH]ncc2c1 Show InChI InChI=1S/C19H22N6O/c1-25(15-5-3-2-4-6-15)18-10-17(20-12-21-18)19(26)23-14-7-8-16-13(9-14)11-22-24-16/h7-12,15H,2-6H2,1H3,(H,22,24)(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	418	n/a	n/a	7.4	30
MERCK SERONO SA US Patent					Assay Description Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...				US Patent US9150519 (2015) BindingDB Entry DOI: 10.7270/Q2H993ZK
					More data for this Ligand-Target Pair