BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 3' and Ligand = 'BDBM50277186'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50277186 ((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Praecis Pharmaceuticals Inc Curated by ChEMBL					Assay Description Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptor				Bioorg Med Chem Lett 19: 369-72 (2008) Article DOI: 10.1016/j.bmcl.2008.11.072 BindingDB Entry DOI: 10.7270/Q2H70FNK
Praecis Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50277186 ((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	14.8	n/a	n/a	n/a	n/a
Praecis Pharmaceuticals Inc Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS binding				Bioorg Med Chem Lett 19: 369-72 (2008) Article DOI: 10.1016/j.bmcl.2008.11.072 BindingDB Entry DOI: 10.7270/Q2H70FNK
Praecis Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair