Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sphingosine-1-phosphate lyase 1' and Ligand = 'BDBM65110'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65110 (US10166249, Example 473 | US9522888, 473) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](COCc3ccsc3)CCc2c1 |r| Show InChI InChI=1S/C22H30NO5PS/c23-22(15-28-29(24,25)26)7-5-21(11-22)20-4-3-18-9-16(1-2-19(18)10-20)12-27-13-17-6-8-30-14-17/h3-4,6,8,10,14,16,21H,1-2,5,7,9,11-13,15,23H2,(H2,24,25,26)/t16-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65110 (US10166249, Example 473 | US9522888, 473) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](COCc3ccsc3)CCc2c1 |r| Show InChI InChI=1S/C22H30NO5PS/c23-22(15-28-29(24,25)26)7-5-21(11-22)20-4-3-18-9-16(1-2-19(18)10-20)12-27-13-17-6-8-30-14-17/h3-4,6,8,10,14,16,21H,1-2,5,7,9,11-13,15,23H2,(H2,24,25,26)/t16-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair