new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Steroid 5-alpha-reductase' and Ligand = 'BDBM50289143'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50289143
PNG
((5R,10R,14S)-17-(2-Hydroxy-1-methyl-ethyl)-10-meth...)
Show SMILES [H][C@@]12CC[C@H](C(C)CO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C(=[N+]=[N-])C(=O)CC[C@]12C
Show InChI InChI=1S/C22H34N2O2/c1-13(12-25)15-6-7-16-14-4-5-18-20(24-23)19(26)9-11-22(18,3)17(14)8-10-21(15,16)2/h13-18,25H,4-12H2,1-3H3/t13?,14-,15+,16-,17-,18-,21+,22+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
35n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Apparent inhibitory activity of the compound was determined against rat prostatic Steroid 5-alpha-reductase type I


Bioorg Med Chem Lett 6: 883-884 (1996)


Article DOI: 10.1016/0960-894X(96)00136-9
BindingDB Entry DOI: 10.7270/Q24B319W
More data for this
Ligand-Target Pair