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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50049341'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50049341
PNG
(CHEMBL350381 | N-{3-(1H-Indol-3-yl)-2-[2-(4-phenyl...)
Show SMILES CCC(=O)N(CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(CC1)c1ccccc1)Cc1ccccc1OC
Show InChI InChI=1S/C34H41N5O3/c1-3-34(41)39(23-26-11-7-10-16-32(26)42-2)24-28(21-27-22-35-31-15-9-8-14-30(27)31)36-33(40)25-37-17-19-38(20-18-37)29-12-5-4-6-13-29/h4-16,22,28,35H,3,17-21,23-25H2,1-2H3,(H,36,40)
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Article
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n/an/a 0.810n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against Tachykinin receptor 1 in human IM-9 cells using [125I]-labeled Boltan-Hunter substance P as radioligand

J Med Chem 39: 736-48 (1996)


Article DOI: 10.1021/jm950616c
BindingDB Entry DOI: 10.7270/Q20864C7
More data for this
Ligand-Target Pair