Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Homo sapiens (Human)) | BDBM50220132 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]SP from human NK1 receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 5310-5 (2007) Article DOI: 10.1016/j.bmcl.2007.08.028 BindingDB Entry DOI: 10.7270/Q2DR2V75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50220132 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]SP from human NK1 receptor expressed in CHO cells in presence of 50% human serum | Bioorg Med Chem Lett 17: 5310-5 (2007) Article DOI: 10.1016/j.bmcl.2007.08.028 BindingDB Entry DOI: 10.7270/Q2DR2V75 | |||||||||||
More data for this Ligand-Target Pair |