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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Succinate receptor 1' and Ligand = 'BDBM50393133'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Succinate receptor 1


(Homo sapiens (Human))		BDBM50393133
PNG
(CHEMBL2153465)
Show SMILES C[C@H](NC(=O)C(C)(C)c1ccc(cc1)-c1ccc2cccnc2n1)c1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F |r|
Show InChI InChI=1S/C33H27F4N3O/c1-20(21-6-8-22(9-7-21)25-12-16-28(34)27(19-25)33(35,36)37)39-31(41)32(2,3)26-14-10-23(11-15-26)29-17-13-24-5-4-18-38-30(24)40-29/h4-20H,1-3H3,(H,39,41)/t20-/m0/s1
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Advinus Therapeutics

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...

Bioorg Med Chem Lett 21: 3596-602 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.091
BindingDB Entry DOI: 10.7270/Q2BK1DG6
More data for this
Ligand-Target Pair