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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Syk protein' and Ligand = 'BDBM50360613'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Syk protein


(Mus musculus)
BDBM50360613
PNG
(CHEMBL1933542)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(C2)C2CCCCC2)c2ccccc12 |r|
Show InChI InChI=1S/C26H28FN3O/c27-19-10-11-22-18(14-19)15-23(28-22)25(31)30-17-26(21-8-4-5-9-24(21)30)12-13-29(16-26)20-6-2-1-3-7-20/h4-5,8-11,14-15,20,28H,1-3,6-7,12-13,16-17H2/t26-/m1/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.79E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA


Bioorg Med Chem Lett 22: 190-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.036
BindingDB Entry DOI: 10.7270/Q2CF9QJS
More data for this
Ligand-Target Pair