BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50068320'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50068320 (2,7-Bis[3-(pyrrolidino)propionamido]anthraquinone ...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity of telomerase was measured using the TRAP assay.				J Med Chem 41: 4873-84 (1998) Article DOI: 10.1021/jm981067o BindingDB Entry DOI: 10.7270/Q2WW7GSD
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50068320 (2,7-Bis[3-(pyrrolidino)propionamido]anthraquinone ...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Defense Medical Center Curated by ChEMBL					Assay Description Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assay				Bioorg Med Chem 16: 6976-86 (2008) Article DOI: 10.1016/j.bmc.2008.05.072 BindingDB Entry DOI: 10.7270/Q27944HS
National Defense Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair