Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50068321'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50068321 (2,7-Bis[3-(piperidino)propionamido]anthraquinone |...) Show SMILES O=C(CCN1CCCCC1)Nc1ccc2C(=O)c3ccc(NC(=O)CCN4CCCCC4)cc3C(=O)c2c1 Show InChI InChI=1S/C30H36N4O4/c35-27(11-17-33-13-3-1-4-14-33)31-21-7-9-23-25(19-21)30(38)26-20-22(8-10-24(26)29(23)37)32-28(36)12-18-34-15-5-2-6-16-34/h7-10,19-20H,1-6,11-18H2,(H,31,35)(H,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity of telomerase was measured using the TRAP assay.				J Med Chem 41: 4873-84 (1998) Article DOI: 10.1021/jm981067o BindingDB Entry DOI: 10.7270/Q2WW7GSD
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50068321 (2,7-Bis[3-(piperidino)propionamido]anthraquinone |...) Show SMILES O=C(CCN1CCCCC1)Nc1ccc2C(=O)c3ccc(NC(=O)CCN4CCCCC4)cc3C(=O)c2c1 Show InChI InChI=1S/C30H36N4O4/c35-27(11-17-33-13-3-1-4-14-33)31-21-7-9-23-25(19-21)30(38)26-20-22(8-10-24(26)29(23)37)32-28(36)12-18-34-15-5-2-6-16-34/h7-10,19-20H,1-6,11-18H2,(H,31,35)(H,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity against telomerase				J Med Chem 42: 2679-84 (1999) Article DOI: 10.1021/jm990084q BindingDB Entry DOI: 10.7270/Q2DF6RX9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50068321 (2,7-Bis[3-(piperidino)propionamido]anthraquinone |...) Show SMILES O=C(CCN1CCCCC1)Nc1ccc2C(=O)c3ccc(NC(=O)CCN4CCCCC4)cc3C(=O)c2c1 Show InChI InChI=1S/C30H36N4O4/c35-27(11-17-33-13-3-1-4-14-33)31-21-7-9-23-25(19-21)30(38)26-20-22(8-10-24(26)29(23)37)32-28(36)12-18-34-15-5-2-6-16-34/h7-10,19-20H,1-6,11-18H2,(H,31,35)(H,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Defense Medical Center Curated by ChEMBL					Assay Description Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assay				Bioorg Med Chem 16: 6976-86 (2008) Article DOI: 10.1016/j.bmc.2008.05.072 BindingDB Entry DOI: 10.7270/Q27944HS
					More data for this Ligand-Target Pair