Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50104470'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50104470 (CHEMBL431613 | [(R)-1-[(R)-1-{12-[(2-Chloro-phenox...) Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H59ClN5O8P/c1-45(2,3)58-44(54)51-40(30-34-28-32-20-12-15-23-37(32)49-34)43(53)50-39(29-33-31-48-38-24-16-13-21-35(33)38)42(52)47-26-18-10-8-6-4-5-7-9-11-19-27-57-60(55,56)59-41-25-17-14-22-36(41)46/h12-17,20-25,28,31,39-40,48-49H,4-11,18-19,26-27,29-30H2,1-3H3,(H,47,52)(H,50,53)(H,51,54)(H,55,56)/t39-,40-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory activity against telomerase extracted from HCT 116 cell lines				Bioorg Med Chem Lett 11: 2581-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD10Z2
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