Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50104490'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50104490 (CHEMBL314864 | [(R)-1-{12-[(2-Chloro-phenoxy)-hydr...) Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)Oc1ccccc1Cl Show InChI InChI=1S/C37H47ClN3O7P/c38-32-21-13-15-23-35(32)48-49(44,45)47-25-17-8-6-4-2-1-3-5-7-16-24-39-36(42)34(26-30-27-40-33-22-14-12-20-31(30)33)41-37(43)46-28-29-18-10-9-11-19-29/h9-15,18-23,27,34,40H,1-8,16-17,24-26,28H2,(H,39,42)(H,41,43)(H,44,45)/t34-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory activity against telomerase extracted from HCT 116 cell lines				Bioorg Med Chem Lett 11: 2581-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD10Z2
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