Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50111322'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50111322 (CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...) Show SMILES CN(C)CCCNc1nc2ccccc2c2[nH]c3c(ccc4ccc(cc34)[N+]([O-])=O)c12 Show InChI InChI=1S/C24H23N5O2/c1-28(2)13-5-12-25-24-21-18-11-9-15-8-10-16(29(30)31)14-19(15)22(18)27-23(21)17-6-3-4-7-20(17)26-24/h3-4,6-11,14,27H,5,12-13H2,1-2H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Tested for inhibitory activity against Telomerase in telomerase repeat amplification protocol (TRAP) assay				Bioorg Med Chem Lett 12: 1071-4 (2002) BindingDB Entry DOI: 10.7270/Q2RJ4HS0
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50111322 (CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...) Show SMILES CN(C)CCCNc1nc2ccccc2c2[nH]c3c(ccc4ccc(cc34)[N+]([O-])=O)c12 Show InChI InChI=1S/C24H23N5O2/c1-28(2)13-5-12-25-24-21-18-11-9-15-8-10-16(29(30)31)14-19(15)22(18)27-23(21)17-6-3-4-7-20(17)26-24/h3-4,6-11,14,27H,5,12-13H2,1-2H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128862 BindingDB Entry DOI: 10.7270/Q2KH0S85
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50111322 (CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...) Show SMILES CN(C)CCCNc1nc2ccccc2c2[nH]c3c(ccc4ccc(cc34)[N+]([O-])=O)c12 Show InChI InChI=1S/C24H23N5O2/c1-28(2)13-5-12-25-24-21-18-11-9-15-8-10-16(29(30)31)14-19(15)22(18)27-23(21)17-6-3-4-7-20(17)26-24/h3-4,6-11,14,27H,5,12-13H2,1-2H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi"Magna Gr£cia" Curated by ChEMBL					Assay Description Inhibition of telomerase (unknown origin) by TRAP assay				Eur J Med Chem 68: 139-49 (2013) Article DOI: 10.1016/j.ejmech.2013.07.022 BindingDB Entry DOI: 10.7270/Q24J0GJB
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50111322 (CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...) Show SMILES CN(C)CCCNc1nc2ccccc2c2[nH]c3c(ccc4ccc(cc34)[N+]([O-])=O)c12 Show InChI InChI=1S/C24H23N5O2/c1-28(2)13-5-12-25-24-21-18-11-9-15-8-10-16(29(30)31)14-19(15)22(18)27-23(21)17-6-3-4-7-20(17)26-24/h3-4,6-11,14,27H,5,12-13H2,1-2H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	5.01E+8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of telomerase (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-011-9594-4 BindingDB Entry DOI: 10.7270/Q2X63QV3
					More data for this Ligand-Target Pair