Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50298378'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50298378 (CHEMBL573120 | N,N'-[4,5-Acridindiylbis(methylene)...) Show SMILES O=C(CCCN1CCCC1)NCc1cccc2cc3cccc(CNC(=O)CCCN4CCCC4)c3nc12 Show InChI InChI=1S/C31H41N5O2/c37-28(13-7-19-35-15-1-2-16-35)32-22-26-11-5-9-24-21-25-10-6-12-27(31(25)34-30(24)26)23-33-29(38)14-8-20-36-17-3-4-18-36/h5-6,9-12,21H,1-4,7-8,13-20,22-23H2,(H,32,37)(H,33,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims-Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human telomerase in A549 cells by TRAP assay				Eur J Med Chem 44: 3880-8 (2009) Article DOI: 10.1016/j.ejmech.2009.04.021 BindingDB Entry DOI: 10.7270/Q2W37WDH
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