Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50376747 (CHEMBL409247) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut National de la Sant£ et de la Recherche M£dicale Curated by ChEMBL | Assay Description Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assay | Proc Natl Acad Sci USA 104: 17347-52 (2007) Article DOI: 10.1073/pnas.0707365104 BindingDB Entry DOI: 10.7270/Q26974FQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50376747 (CHEMBL409247) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut National de la Sant£ et de la Recherche M£dicale Curated by ChEMBL | Assay Description Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assay | Proc Natl Acad Sci USA 104: 17347-52 (2007) Article DOI: 10.1073/pnas.0707365104 BindingDB Entry DOI: 10.7270/Q26974FQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50376747 (CHEMBL409247) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut National de la Sant£ et de la Recherche M£dicale Curated by ChEMBL | Assay Description Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assay | Proc Natl Acad Sci USA 104: 17347-52 (2007) Article DOI: 10.1073/pnas.0707365104 BindingDB Entry DOI: 10.7270/Q26974FQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50376747 (CHEMBL409247) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut National de la Sant£ et de la Recherche M£dicale Curated by ChEMBL | Assay Description Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assay | Proc Natl Acad Sci USA 104: 17347-52 (2007) Article DOI: 10.1073/pnas.0707365104 BindingDB Entry DOI: 10.7270/Q26974FQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50376747 (CHEMBL409247) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut National de la Sant£ et de la Recherche M£dicale Curated by ChEMBL | Assay Description Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assay | Proc Natl Acad Sci USA 104: 17347-52 (2007) Article DOI: 10.1073/pnas.0707365104 BindingDB Entry DOI: 10.7270/Q26974FQ | |||||||||||
More data for this Ligand-Target Pair |