Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidylate synthase (Homo sapiens (Human)) | BDBM50314076 (5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University of the Holy Ghost US Patent | Assay Description Inhibition of various kinase enzyme. | US Patent US9422297 (2016) BindingDB Entry DOI: 10.7270/Q2MC8XX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Homo sapiens (Human)) | BDBM50314076 (5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of human thymidylate synthase | J Med Chem 53: 1563-78 (2010) Article DOI: 10.1021/jm9011142 BindingDB Entry DOI: 10.7270/Q2SX6F6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Escherichia coli) | BDBM50314076 (5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University of the Holy Ghost US Patent | Assay Description Inhibition of various kinase enzyme. | US Patent US9422297 (2016) BindingDB Entry DOI: 10.7270/Q2MC8XX9 | |||||||||||
More data for this Ligand-Target Pair |