new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor' and Ligand = 'BDBM18882'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thyroid hormone receptor


(Homo sapiens (Human))
BDBM18882
PNG
((2S)-2-(1-{3,5-dibromo-4-[4-hydroxy-3-methyl-5-(pr...)
Show SMILES CC(C)[C@H](NC(=O)Cc1cc(Br)c(Oc2cc(C)c(O)c(c2)C(C)C)c(Br)c1)C(O)=O |r|
Show InChI InChI=1S/C23H27Br2NO5/c1-11(2)16-10-15(6-13(5)21(16)28)31-22-17(24)7-14(8-18(22)25)9-19(27)26-20(12(3)4)23(29)30/h6-8,10-12,20,28H,9H2,1-5H3,(H,26,27)(H,29,30)/t20-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/a 170n/an/a7.04



Karo Bio AB



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...


Bioorg Med Chem Lett 17: 4131-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.049
BindingDB Entry DOI: 10.7270/Q2VT1QB6
More data for this
Ligand-Target Pair