Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tissue-type plasminogen activator (Homo sapiens (Human)) | BDBM14059 (4-hydroxy-3-[[(3S)-2-oxo-3-(9-thia-5-azabicyclo[4....) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Curated by ChEMBL | Assay Description Binding affinity against tissue plasminogen activator (t-Pa) | Bioorg Med Chem Lett 9: 2753-8 (1999) BindingDB Entry DOI: 10.7270/Q2W66K02 | |||||||||||
More data for this Ligand-Target Pair |