Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tissue-type plasminogen activator (Homo sapiens (Human)) | BDBM17643 ((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of tissue plasminogen activator by fluorogenic assay | Bioorg Med Chem Lett 17: 2927-30 (2007) Article DOI: 10.1016/j.bmcl.2007.03.080 BindingDB Entry DOI: 10.7270/Q22V2FTR | |||||||||||
More data for this Ligand-Target Pair |