Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM50003738'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50003738 ((lactone 2)N-[4-(6-Iodomethylene-2-oxo-tetrahydro-...) Show SMILES NC(=N)NCc1ccc(cc1)C1CC\C(OC1=O)=C\I Show InChI InChI=1S/C14H16IN3O2/c15-7-11-5-6-12(13(19)20-11)10-3-1-9(2-4-10)8-18-14(16)17/h1-4,7,12H,5-6,8H2,(H4,16,17,18)/b11-7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois Curated by ChEMBL					Assay Description Compound was tested for its binding affinity against the enzyme Tissue plasminogen activator				J Med Chem 35: 4297-305 (1992) BindingDB Entry DOI: 10.7270/Q2TD9W9D
					More data for this Ligand-Target Pair