Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM273251'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273251 (2-(4-(3-isopropyl-2-(8-methoxy-[1,2,4]triazolo[1,5...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N(C)C)CC1 Show InChI InChI=1S/C27H34N6O2/c1-17(2)25-21-12-19(18-8-10-32(11-9-18)15-24(34)31(3)4)6-7-22(21)30-26(25)20-13-23(35-5)27-28-16-29-33(27)14-20/h6-7,12-14,16-18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273251 (2-(4-(3-isopropyl-2-(8-methoxy-[1,2,4]triazolo[1,5...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N(C)C)CC1 Show InChI InChI=1S/C27H34N6O2/c1-17(2)25-21-12-19(18-8-10-32(11-9-18)15-24(34)31(3)4)6-7-22(21)30-26(25)20-13-23(35-5)27-28-16-29-33(27)14-20/h6-7,12-14,16-18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair