Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM273769'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273769 (US10071079, Example 555 | US10478424, Example 555) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC2(C)COC2)CC1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C28H32F3N5O/c1-17(2)24-21-10-19(18-6-8-35(9-7-18)13-27(3)14-37-15-27)4-5-23(21)34-25(24)20-11-22(28(29,30)31)26-32-16-33-36(26)12-20/h4-5,10-12,16-18,34H,6-9,13-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273769 (US10071079, Example 555 | US10478424, Example 555) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC2(C)COC2)CC1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C28H32F3N5O/c1-17(2)24-21-10-19(18-6-8-35(9-7-18)13-27(3)14-37-15-27)4-5-23(21)34-25(24)20-11-22(28(29,30)31)26-32-16-33-36(26)12-20/h4-5,10-12,16-18,34H,6-9,13-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair