Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM273856'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273856 (US10071079, Example 642 | US10478424, Example 642) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(C)C)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C27H31F3N6O/c1-16(2)24-20-11-18(17-7-9-35(10-8-17)23(37)14-34(3)4)5-6-22(20)33-25(24)19-12-21(27(28,29)30)26-31-15-32-36(26)13-19/h5-6,11-13,15-17,33H,7-10,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273856 (US10071079, Example 642 | US10478424, Example 642) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(C)C)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C27H31F3N6O/c1-16(2)24-20-11-18(17-7-9-35(10-8-17)23(37)14-34(3)4)5-6-22(20)33-25(24)19-12-21(27(28,29)30)26-31-15-32-36(26)13-19/h5-6,11-13,15-17,33H,7-10,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair