Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM273981'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273981 (US10071079, Example 767 | US10478424, Example 767) Show SMILES CC(C)N(C)CC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C30H40N6O/c1-18(2)28-24-14-23(22-10-12-35(13-11-22)27(37)16-34(7)19(3)4)8-9-26(24)33-29(28)25-15-36-30(31-17-32-36)21(6)20(25)5/h8-9,14-15,17-19,22,33H,10-13,16H2,1-7H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273981 (US10071079, Example 767 | US10478424, Example 767) Show SMILES CC(C)N(C)CC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C30H40N6O/c1-18(2)28-24-14-23(22-10-12-35(13-11-22)27(37)16-34(7)19(3)4)8-9-26(24)33-29(28)25-15-36-30(31-17-32-36)21(6)20(25)5/h8-9,14-15,17-19,22,33H,10-13,16H2,1-7H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair